Disease: Cerebrovascular Disorders
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VWF P04275 von Willebrand factor Enzyme modulator 3.2E-25 0.408 0.885
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
VCAM1 P19320 vascular cell adhesion molecule 1 0.80 0.422 0.808
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
SELP P16109 selectin P 5.0E-32 0.460 0.769
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PLA2G7 Q13093 phospholipase A2 group VII Enzyme 5.3E-22 0.537 0.769
PECAM1 P16284 platelet and endothelial cell adhesion molecule 1 Cell adhesion 0.426 0.846
NPPA P01160 natriuretic peptide A 5.5E-04 0.505 0.769
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885
LOX P28300 lysyl oxidase 0.99 0.447 0.846
IL6 P05231 interleukin 6 0.32 0.248 0.962
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
FGA P02671 fibrinogen alpha chain 1.2E-13 0.573 0.769
F2 P00734 coagulation factor II, thrombin Enzyme 1.1E-03 0.415 0.885
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923
EDNRB P24530 endothelin receptor type B G-protein coupled receptor 9.2E-03 0.470 0.846